Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
we will explore some of the potential pitfalls of Sober October, including the Alcohol Deprivation Effect, the dangers of sudden cessation of alcohol, and the neuroscience behind addiction.
In this blog post, we will explore what pharmacological extinction entails, how it works in conjunction with the Sinclair Method, and its implications for those seeking to Rethink Drink.
The Sinclair Method (TSM) represents a ground-breaking shift in the treatment of Alcohol Use Disorder (AUD), offering hope and a new lease on life for many who struggle with alcohol dependency.